The most important Ecuador's port, this city is a good departure point or gateway for the Galapagos. The most populous and active city in Ecuador, Guayaquil is Ecuador's commercial center. Shopping bargains abound. Rich and varied seafood is a culinary specialty. Las Penas neighborhood preserves the colonial period at its best. Guayaquil is the natural gateway to beautiful beaches and nautical sports, and offers great entertainment with its many restaurants, nightclubs, and casinos.